NAVAL AIDS RESEARCH CENTER | UNIT OF INDIAN SOCIAL SERVICE

HIV/AIDS Knowledge Center

HIV/AIDS KNOWLEDGE CENTER

Global learning place for resource, knowledge, information, education and research on HIV and AIDS

My concept is coming out now with real and true examples with the research of other researchers, scientists and doctors. Recently the “Esperanza patient,” patient proved my concept that the HIV, Cancer and many viral diseases could be cured by stimulating our body’s its own immune system. Some will get stimulated spontaneously (rare cases) and some has to be stimulated with suitable immune therapy. For the spontaneous immune system stimulation this is the example.

https://www.nbcnews.com/health/health-news/womans-immune-system-possibly-cured-hiv-rcna5610?fbclid=IwAR1w5MYzObE1XCoi9csQg2ke256XFo9MxhFf5qZ4RFSpe57Asx_XrSIRYtE

The details about the already cured patients other than our centre

1.London Patient (2019)

Type of cure declared: Remission, functional’ cure

Type of intervention: Stem cell transplantation with two copies of the CCR5 delta-32 gene

2. Berlin Patient (2008)

Timothy Brown, also known as the Berlin Patient.

Type of cure declared: Remission, functional’ cure

Type of intervention: Stem cell transplantation, two stem cell transplants and total body irradiation

3. Mississippi Baby (2013)

Type of cure declared: Functional cure

Type of intervention: The baby was given a strong dose of three antiretroviral drugs soon after birth, but their treatment stopped abruptly at 18 months when the mother was lost from care. When mother and baby returned to care five months later, the baby’s viral load was undetectable.

But just one year later, the landmark case took a significant blow when detectable levels of HIV were found again in the baby. Hence why, in cases such as the London patient, scientists are hesitant to declare a cure.

4. French Teenager (2015)

HIV remission case with ART

5. Visconti group (2012)

In a 2012 study, 14 French people living with HIV known as the ‘Visconti cohort’, started taking ART within 10 weeks of infection. After three years of medication, they stopped taking treatment, which would normally result in HIV re-emerging. Remarkably, they maintained low levels of HIV in their systems for an average of seven years before a recurrence of the virus emerged.


What does all this mean?

Our patients are performing well with our Prakasine immunotherapy. If we get funding and support we can publish more cases like above

1.HIV basics

  The basics for the HIV infection is, the gp120 receptor of the virus and the CD4 receptor of the host cell should get attached

2.What are HIV and AIDS

  HIV is the infective stage of the person with HIV virus when we talk about the person regard to HIV, otherwise it will mean only Human Immunodeficiency Virus. Likewise, the AIDS is the stage with the minimum to maximum opportunistic infections due to reduction of immunity or reduced functions of immune system created by the virus.

3. HIV/AIDS

  Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). By damaging your immune system, HIV interferes with your body’s ability to fight infection and disease.

4.HIV and AIDS

  HIV (human immunodeficiency virus) is a virus that attacks cells that help the body fight infection, making a person more vulnerable to other infections and diseases. It is spread by contact with certain bodily fluids of a person with HIV, most commonly during unprotected sex (sex without a condom or HIV medicine to prevent or treat HIV), or through sharing injection drug equipment.

  If left untreated, HIV can lead to the disease AIDS (acquired immunodeficiency syndrome).

  The human body can’t get rid of HIV and no effective HIV cure exists. So, once you have HIV, you have it for life.

  AIDS is the late stage of HIV infection that occurs when the body’s immune system is badly damaged because of the virus.

5.What is HIV and AIDS

  Ultimately, HIV is a virus that attacks the immune system and AIDS is a term that can only be used when HIV has caused severe damage to the immune system

6.HIV infection

  HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). Learning the basics about   HIV can keep you healthy and prevent HIV transmission. You can also download materials to share or watch videos on basic information about HIV.

7.Immune system and HIV cure

  It is possible that an equally strong immune response in combination with powerful drugs could have cured the HIV completely, however this is far from certain.

8.HIV treatment

  Normally, the world wide treatment is as per CDC

  HIV treatment involves taking medicine that reduces the amount of HIV in your body.

  HIV medicine is called antiretroviral therapy (ART).

  There is no effective cure for HIV. But with proper medical care, you can control HIV.

  Most people can get the virus under control within six months.

  Taking HIV medicine does not prevent transmission of other sexually transmitted diseases.

9.HIV Treatment overview

  HIV treatment involves taking medicines that slow the progression of the virus in your body. HIV is a type of virus called a retrovirus, and the combination of drugs used to treat it is called antiretroviral therapy (ART). ART is recommended for all people living with HIV, regardless of how long they’ve had the virus or how healthy they are. ART must be taken every day, exactly as your health care provider prescribes.

10.Treatment for HIV/ AIDS

  Tests to stage disease and treatment

  If you’ve been diagnosed with HIV, it’s important to find a specialist trained in diagnosing and treating HIV to help you:

  • Determine whether you need additional testing
  • Determine which HIV antiretroviral therapy (ART) will be best for you
  • Monitor your progress and work with you to manage your health

  If you receive a diagnosis of HIV/AIDS, several tests can help your doctor determine the stage of your disease and the best treatment, including:

  • CD4 T cell count. CD4 T cells are white blood cells that are specifically targeted and destroyed by HIV. Even if you have no symptoms, HIV infection progresses to AIDS when your CD4 T cell count dips below 200.
  • Viral load (HIV RNA). This test measures the amount of virus in your blood. After starting HIV treatment the goal is to have an undetectable viral load. This significantly reduces your chances of opportunistic infection and other HIV-related complications.
  • Drug resistance. Some strains of HIV are resistant to medications. This test helps your doctor determine if your specific form of the virus has resistance and guides treatment decisions.

  Tests for complications

Your doctor might also order lab tests to check for other infections or complications, including:

  • Tuberculosis
  • Hepatitis B or hepatitis C virus infection
  • STIs
  • Liver or kidney damage
  • Urinary tract infection
  • Cervical and anal cancer
  • Cytomegalovirus
  • Toxoplasmosis

11. HIV and AIDS : Symptoms, causes, Diagnosis and Treatment

  As the virus continues to multiply and destroy your immune cells — the cells in your body that help fight off germs — you may develop mild infections or chronic signs and symptoms such as: Fever. Fatigue. Swollen lymph nodes — often one of the first signs of HIV infection.

12. HIV/AIDS medicine I HIV Cure I HIV Treatment

  HIV medicine is called antiretroviral therapy (ART). The whole world is saying there is no effective cure for HIV. But with proper medical care, you can control HIV. Most people can get the virus under control within six months. There is possible to cure with deep research as what we do.

13. ART Treatment

  The treatment for HIV is called antiretroviral therapy (ART). ART involves taking a combination of HIV medicines (called an HIV treatment regimen) every day. ART is recommended for everyone who has HIV. ART cannot cure HIV, but HIV medicines help people with HIV live longer, healthier lives.

14. Antiretroviral drugs for treatment and prevention of HIV.

  Data on the use of antiretroviral drugs, including new drugs and formulations, for the treatment and prevention of HIV infection continue to guide optimal practices. We suggest along with our immunotherapy.

15. Cure HIV positive

  The whole world was thinking that the human body can’t get rid of HIV and no effective HIV cure exists. But now it has been proven in support of my concept in the settings of Tertiary care centers in Buenos Aires, Argentina, and Boston, Massachusetts by increasing the our own immune system against the virus. What I said 30 years back as an independent researcher now the people in threading institutes proved my concept as “A woman in Argentina has become only the second documented person whose own immune system may have cured her of HIV.

Researchers have dubbed the 30-year-old mother, who was first diagnosed with HIV in 2013, the “Esperanza patient,” after the town in Argentina where she lives. In English, “esperanza” means “hope.”

16. First, second, third and subsequent cures in our centre

  First person to cure from HIV on 2006. The second person to cure from HIV on 2010. Third person to cure from HIV on 2010, subsequent cures achieved in our center with our immunotherapy approach.

17. Starting HIV treatment

  Start Treatment As Soon As Possible After Diagnosis · HIV medicine is recommended for all people with HIV, regardless of how long they’ve had the virus

18. HIV treatment evaluation

  Patient evaluation and with treatment for adults and adolescents is necessary.

19. HIV treatment and an undetectable viral load to prevent HIV

  An undetectable viral load is where antiretroviral treatment (ART) has reduced your HIV to such small quantities that it can no longer be detected by standard blood tests. People living with HIV who have an undetectable viral load cannot pass HIV on through sex. Being undetectable does not mean your HIV is cured.

20. HIV Treatment prevention

  HIV Treatment as Prevention. A highly effective strategy to prevent the sexual transmission of HIV and with preventive medications for the suspectable risky people.

21. India to provide freee treatment for all people living with HIV

  On 28 April,2017, during an event in New Delhi, Jagat Prakash Nadda, the Minister of Health and Family Welfare, announced a new test-and-treat policy that commits to providing access to HIV treatment for everyone living with HIV in the country.

22. HIV treatment to all who need it in Tamilnadu, India and from people in various countries in world can reach us

  They can come to our centre for consulting, treatment and testing

23. Our treatment shows significant reduction in death and patients are leading a healthy life?

  Yes, Our treatment shows significant reduction in death and patients are leading a healthy life?

24. Best HIV/ AIDS treatment and research center

  We are doing it to our level best by giving dedicated research out come to the patients

25. HIV/AIDS treatment and prevention in India

  We are doing it

26. Corona virus and HIV

  We are doing it

27. Our treatment- less to nil side effects

  Our treatment has less to nil side effects

28. HIV in India

  The HIV in India is more prevalence

29. Complete cure for HIV

  Possible by our research out come

30. World AIDS Day – Naval AIDS Research center, Tamilnadu, India (post in blog with image)

  On World AIDS day we are rendering our services to poor and needy by providing free consultation, Councelling and performing advanced testings for HIV at lowest prices to the required persons.

31. Do we have patients from India and from abroad?

  Yes, we have patients from India and from abroad

32. Novel HIV treatment

  Our treatment is Novel because we use our innovative immunotherapy without any side effects

33. Care, support and treatment for HIV for people (in Tamilnadu, India and various parts of the world)

  We are giving it through our eminent team

34. HIV/AIDS complete cure

  Yes, possible with my concept. Recently the “Esperanza patient,” patient is the proof of our concept

35. Fight against HIV

  Whole world is fighting against the HIV to bring this HIV pandemic into an end. UNAIDS and International AIDS Society is also taking various measures in Combating this HIV virus. Every year International AIDS Society is organizing the conferences for HIV in different countries by bringing the eminent and leading scientist working in HIV cure research.

36. HIV infected cases in India? HIV infected cases in Tamilnadu?

  Around  23.49 lakh people in India living with HIV/AIDS (PLHIV) in 2019

  Around 2.2 lakh people in Tamil Nadu are living with HIV/AIDS in 2021 as per TANSACS

  Around 3.14 lakhs people living in Andhra Pradesh with HIV/AIDS in 2019

  Around 0.24 lakhs people living in Kerala with HIV/AIDS in 2019

  Around 2.69 lakhs people living in Karnataka with HIV/AIDS in 2019

  Around 3.96 lakhs people living in Maharashtra with HIV/AIDS in 2019

  Around 0.68 lakhs people living in Delhi with HIV/AIDS in 2019

  Around 1.04 lakhs people living in Gujarat with HIV/AIDS in 2019

  Around 1.34 lakhs people living in Bihar with HIV/AIDS in 2019

37. HIV infected cases in world wide? HIV infected cases in Africa? HIV infected cases in Europe? HIV infected cases in America? HIV infected cases in UK? HIV infected cases in Russia? & HIV infected cases in other parts of the world?

According to UNAIDS : Number of People with HIV—There were approximately 37.6 million people across the globe with HIV in 2020. Of these, 35.9 million were adults and 1.7 million were  children (<15 years old).

East and Southern Africa remains the region most affected by HIV/AIDS in the world, with 20.7 million people living with HIV and 730,000 new HIV infections in 2019

2,2 million people living with HIV in Western & Central Europe and North America till 2019

Approximately 1.2 million people in the U.S

In 2019, it was estimated that there are 105,200 people living with HIV in the UK.

    1. million and 1.4 million Russians are infected & living with HIV.

As of 2019, the Ministry of Health estimated that there were 87,581 people living with HIV (PLHIV) in Malaysia.

In 2019, it was estimated that approximately 3.6 thousand people in Sri Lanka were living with HIV.

38) HIV around the world

1. Eswatini

Swaziland (Eswatini) has the highest HIV prevalence and incidence of any country in the world of 27%.

2. Lesotho

Lesotho has the second-highest HIV rate in the world of 25%.

3. Botswana

The country with the third-highest HIV prevalence is Botswana, with an estimated 21.90% of the population diagnosed. About 370,000 people in Botswana are living with HIV.

4. South Africa

The HIV prevalence in South Africa is 18.90%, making it the fourth-highest rate in the world. There are 7.7 million people living with HIV in South Africa, the largest HIV epidemic in the world. In 2018, South Africa saw 240,000 new HIV infections.

5. Namibia

Namibia has the fifth-highest rate of HIV in the world of 13.80%. About 200,000 people in Namibia are living with HIV with about 6,100 newly infected individuals in 2018.

6. Zimbabwe

Zimbabwe’s HIV rate is 13.50%, the sixth-highest in the world. There are 1.3 million people living with HIV in Zimbabwe.

7. Zambia

Zambia has the seventh-highest HIV rate in the world of 12.40%. 1.2 million people in Zambia have HIV.

8. Mozambique

Mozambique’s HIV rate is 12.30%, the eighth-highest in the world. As of 2018, 2.2 million people live with HIV in Mozambique with 150,000 people newly infected. Women are disproportionately affected by HIV in Mozambique: about 60% of the adults living with HIV are women and new HIV infections among young women (ages 15-24) were almost double those among young men.

9. Malawi

Malawi is the first country on the list whose HIV rate is below 10% at 9.20%. This rate is the ninth-highest in the world. About 1 million people live with HIV in Malawi.

10. Uganda

Uganda has the tenth-highest HIV rate in the world of 6.50%. 1.4 million people in Uganda live with HIV.

39. About the HIV/AIDS

HIV causes AIDS and interferes with the body’s ability to fight infections.

The virus can be transmitted through contact with infected blood, semen or vaginal fluids.

Within a few weeks of HIV infection, flu-like symptoms such as fever, sore throat and fatigue can occur. Then the disease is usually asymptomatic until it progresses to AIDS. AIDS symptoms include weight loss, fever or night sweats, fatigue and recurrent infections.

No cure exists for AIDS, but strict adherence to antiretroviral regimens (ARVs) can dramatically slow the disease’s progress as well as prevent secondary infections and complications.

40. Treatment for HIV and AIDS

We are giving it to our level best

41. Best Treatment for HIV

We are giving it to our level best

42. Permanent cure for HIV

Yes, it is possible in our center


Glossary

Adherence

Adherence means taking HIV treatment exactly as you are advised to by your healthcare professional (including what time of day, how often, with or without food, and so on). Poor adherence can lead to drug resistance which means your treatment will stop working. It’s particularly important to make sure you don’t run out of drugs, as a break in treatment is dangerous.

AIDS

AIDS stands for Acquired Immune Deficiency Syndrome and is a set of symptoms and illnesses that occur at the very final stage of HIV infection. It’s diagnosed when someone’s immune system is severely damaged, and can no longer fight off infections. AIDS and HIV are not the same.

Antiretroviral drugs (ARVs)

ARVs are drugs used to treat HIV and stop it from replicating in the body. ARVs keep the virus at a low level in the body, strengthen the immune system, and reduce the likelihood of passing HIV on. Effective treatment can reduce the virus to undetectable levels.

Antiretroviral treatment (ART)

ART is the treatment for HIV – a combination of three or more antiretroviral drugs that target different stages of the HIV lifecycle.

CD4 count

Your CD4 count is the number of CD4 cells (or T-helper cells) in your blood, measured by a simple blood test. This tells you how healthy your immune system is – your CD4 count should go up when you have HIV treatment. It’s often talked about at the same time as viral load (the amount of HIV virus in your blood). Generally when your CD4 count is high, your viral load is low and vice versa.

Chemsex

Chemsex involves using drugs to enhance sex. It can involve groups (including larger party settings), couples or lone masturbation. The main drugs used for chemsex are GHB, mephedrone and crystal meth.

Circumcision

Circumcision is the removal of the foreskin from the penis.

Voluntary medical male circumcision (VMMC) reduces the risk of HIV for men who have sex with women by 60%. The World Health Organization and UNAIDS recommend VMMC as an HIV prevention tool in countries with a high HIV prevalence among the general population – mainly in East and Southern Africa.

Co-infection

Co-infection is when someone has more than one serious infection at the same time. For example, when a person with HIV also has tuberculosis (TB), they are said to have an HIV/TB co-infection.   This can make treatment for both infections more difficult, but also more important.

Comorbidity

Comorbidity describes someone who has two or more diseases or health conditions at a time. For example, a person with HIV may also have high blood pressure.

Contraception

Contraception helps couples to avoid getting pregnant or plan when to get pregnant. There are many different types, including hormonal, long-acting reversible contraception and condoms.

Digital health

Digital health refers to the use of digital technologies to deliver or enhance health services and information.

Disclosure 

When a person tells someone that they’re HIV-positive. Although the word ‘disclosure’ has been used for a long time, it is now preferable to use the words ‘sharing’ or ‘telling’. This is because ‘disclosing’ can often reinforce stigmatising beliefs that a person has done something wrong if they are living with HIV.

Drug resistance

If someone with HIV doesn’t take their antiretroviral treatment properly, the drugs may become unable to control the virus, which can cause the treatment to stop working – this is called drug resistance. It’s also possible for someone who has developed a drug-resistant strain of HIV to pass it on.

False negative result

A false negative result is when a person has HIV but an HIV test shows that they don’t have it. A false negative result usually happens during the window period immediately after initial infection, before current tests are able to detect it. If you test negative but think you may have HIV, you can take another test once the window period has passed.

False positive result

A false positive result is when a person does not have HIV but an HIV test shows that they do. Whenever someone receives a positive test result, they are tested again to confirm the result.

Female condom (internal condom)

A female (or internal) condom is a thin pouch that is worn inside the vagina or anus during sex. It works by forming a barrier to protect against sexually transmitted infections (STIs) including HIV, and unplanned pregnancy.

First-line treatment

First-line treatment is the antiretroviral treatment recommended for people starting HIV treatment for the first time. It’s a combination of three or more antiretroviral drugs from two different drug classes.

HIV

HIV stands for Human Immunodeficiency Virus. It attacks a person’s immune system cells, and if left untreated severely damages their immune system and their ability to fight off infections.

HIV cure

There is no cure for HIV. However, antiretroviral treatment can control the virus, meaning that people with HIV can live long and healthy lives.

HIV vaccine

There isn’t a vaccine for HIV but a number of HIV vaccine trials show encouraging results.

Male condom (external condom)

A male (or external) condom is a thin piece of rubbery material that fits over a man’s penis during sex. It works by forming a barrier to protect against sexually transmitted infections (STIs) including HIV, and unplanned pregnancy.

Mixed-status couple

A mixed-status couple is when one person has HIV and the other does not. It is also known as a serodiscordant couple, a discordant couple, or a serodifferent couple.

Post-exposure Prophylaxis (PEP)

PEP is short-term treatment that stops HIV spreading throughout the body. It must be taken within 72 hours of possible exposure to HIV, for example, after unprotected sex, to be effective.

Pre-exposure Prophylaxis (PrEP)

PrEP is a course of antiretroviral drugs that can prevent HIV infection. It’s for men and women who are HIV-negative but who may be at higher risk of HIV infection. For example, someone who has an HIV-positive partner, or is unable to negotiate condom use, or has regular sex without a condom may benefit from PrEP. When PrEP is adhered to exactly as prescribed, it eliminates the risk of HIV infection – but the risk increases significantly if doses are missed.

Opportunistic infection

Opportunistic infections are a type of infection that occur in people with a weakened immune system (for example people living with HIV).

Second-line treatment

When first-line antiretroviral drugs stop working, a person takes second-line treatment.

Self-testing

HIV self-testing allows you to take an HIV test in your own home or another private place. These kits are becoming more widely available and give a result in 15 to 20 minutes.

Syndemic

A syndemic or synergistic epidemic is the combination of two or more coexisting epidemics in a population, for example HIV and TB. Biological interactions between the coexisting epidemics make the prognosis and burden of disease worse.

Sexually transmitted infection (STI)

STIs are infections that can be passed on when you have unprotected sex or close sexual contact with someone who already has an STI. Examples include chlamydia, genital herpes, gonorrhoea, hepatitis C and trichomoniasis. HIV is also a sexually transmitted infection although there are other ways it can be passed on.

T-helper cells

See CD4 count above.

Third-line treatment

When second-line drugs stop working, a person takes third-line treatment.

Undetectable / virally suppressed

A person living with HIV is considered to have an ‘undetectable’ viral load – or to be virally suppressed – when antiretroviral treatment has reduced the virus in their body to such low levels that blood tests cannot detect it. Having an undetectable viral load means you can’t pass HIV onto others, and your health won’t be affected by the virus. It is essential to adhere to treatment and have your viral load monitored by a health professional to make sure it stays undetectable.

Viral load

A person’s viral load is the amount of HIV virus in their blood. It is measured by a simple blood test. It can tell you how well a person’s antiretroviral treatment is working.

Window period

The amount of time it takes after infection for the body to produce enough HIV antibodies to be detected on an HIV test, in order to get an accurate result. This is between 2 and 12 weeks depending on the type of test.

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